Cargando…

Cytosolic BNIP3 Dimer Interacts with Mitochondrial BAX Forming Heterodimers in the Mitochondrial Outer Membrane under Basal Conditions

The primary function of mitochondria is energy production, a task of particular importance especially for cells with a high energy demand like cardiomyocytes. The B-cell lymphoma (BCL-2) family member BCL-2 adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) is linked to mitochondrial targeting afte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hendgen-Cotta, Ulrike B., Esfeld, Sonja, Rudi, Katharina, Miinalainen, Ilkka, Klare, Johann P., Rassaf, Tienush
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412273/ https://www.ncbi.nlm.nih.gov/pubmed/28333095 http://dx.doi.org/10.3390/ijms18040687

Ejemplares similares

S-nitrosation of mitochondrial connexin 43 regulates mitochondrial function
por: Soetkamp, Daniel, et al.
Publicado: (2014)

A novel physiological role for cardiac myoglobin in lipid metabolism
por: Hendgen-Cotta, Ulrike B., et al.
Publicado: (2017)

Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons
por: Leo, Markus, et al.
Publicado: (2020)

The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol
por: Kluck, Ruth M., et al.
Publicado: (1999)

9-PAHSA Prevents Mitochondrial Dysfunction and Increases the Viability of Steatotic Hepatocytes
por: Schultz Moreira, Adriana R., et al.
Publicado: (2020)

The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy
por: Gok, Mehmet Oguz, et al.
Publicado: (2023)

Crosstalk between Nitrite, Myoglobin and Reactive Oxygen Species to Regulate Vasodilation under Hypoxia
por: Totzeck, Matthias, et al.
Publicado: (2014)

A practical approach to remote ischemic preconditioning and ischemic preconditioning against myocardial ischemia/reperfusion injury
por: Totzeck, Matthias, et al.
Publicado: (2016)

Bax Activation Initiates the Assembly of a Multimeric Catalyst that Facilitates Bax Pore Formation in Mitochondrial Outer Membranes
por: Kushnareva, Yulia, et al.
Publicado: (2012)

Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes
por: Gillies, Laura A, et al.
Publicado: (2015)

PD1 Deficiency Modifies Cardiac Immunity during Baseline Conditions and in Reperfused Acute Myocardial Infarction
por: Michel, Lars, et al.
Publicado: (2022)

Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis
por: Große, Lena, et al.
Publicado: (2016)

Raptinal bypasses BAX, BAK, and BOK for mitochondrial outer membrane permeabilization and intrinsic apoptosis
por: Heimer, Sina, et al.
Publicado: (2019)

Superiority of focused ion beam‐scanning electron microscope tomography of cardiomyocytes over standard 2D analyses highlighted by unmasking mitochondrial heterogeneity
por: Heinen‐Weiler, Jacqueline, et al.
Publicado: (2021)

An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial␣membrane
por: Lv, Fujiao, et al.
Publicado: (2021)

Dietary Nitrate Is a Modifier of Vascular Gene Expression in Old Male Mice
por: Rammos, Christos, et al.
Publicado: (2015)

Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane
por: O'Neill, Katelyn L., et al.
Publicado: (2016)

STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
por: Kim, Hyunmi, et al.
Publicado: (2022)

Myocardial Expression of Macrophage Migration Inhibitory Factor in Patients with Heart Failure
por: Pohl, Julia, et al.
Publicado: (2017)

Modulation of Circulating Macrophage Migration Inhibitory Factor in the Elderly
por: Rammos, Christos, et al.
Publicado: (2014)

Renal replacement therapy neutralizes elevated MIF levels in septic shock
por: Pohl, Julia, et al.
Publicado: (2016)

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
por: Karch, Jason, et al.
Publicado: (2013)

Blockade of ß-Adrenergic Receptors by Nebivolol Enables Tumor Control Potential for Uveal Melanoma in 3D Tumor Spheroids and 2D Cultures
por: Farhoumand, Lina S., et al.
Publicado: (2023)

Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation
por: Hung, Victoria, et al.
Publicado: (2017)

A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins
por: Drwesh, Layla, et al.
Publicado: (2022)

Bnip3 as a Dual Regulator of Mitochondrial Turnover and Cell Death in the Myocardium
por: Gustafsson, Åsa B.
Publicado: (2011)

Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy
por: Vianello, Caterina, et al.
Publicado: (2022)

Movement of Bax from the Cytosol to Mitochondria during Apoptosis
por: Wolter, Keith G., et al.
Publicado: (1997)

Filtration of Macrophage Migration Inhibitory Factor (MIF) in Patients with End Stage Renal Disease Undergoing Hemodialysis
por: Luedike, Peter, et al.
Publicado: (2015)

The Adrenergic Receptor Antagonist Carvedilol Elicits Anti-Tumor Responses in Uveal Melanoma 3D Tumor Spheroids and May Serve as Co-Adjuvant Therapy with Radiation
por: Farhoumand, Lina S., et al.
Publicado: (2022)

Correction: Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation
por: Hung, Victoria, et al.
Publicado: (2019)

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy
por: Li, Ermin, et al.
Publicado: (2020)

The Proapoptotic Protein BNIP3 Interacts with VDAC to Induce Mitochondrial Release of Endonuclease G
por: Zhang, Xiaosha, et al.
Publicado: (2014)

Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy
por: Vianello, Caterina, et al.
Publicado: (2022)

Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy
por: Vianello, Caterina, et al.
Publicado: (2023)

Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy
por: Vianello, Caterina, et al.
Publicado: (2023)

Differential Processing of Cytosolic and Mitochondrial Caspases
por: Yuan, Hua, et al.
Publicado: (2001)

The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation
por: Lauterwasser, Joachim, et al.
Publicado: (2016)

Cytosolic Ku70 regulates Bax-mediated cell death
por: Hada, Manila, et al.
Publicado: (2016)

Percutaneous Mitral Valve Repair in Mitral Regurgitation Reduces Cell-Free Hemoglobin and Improves Endothelial Function
por: Rammos, Christos, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_qblhfr4ac372dujkh35vnvk5ph