Cargando…
The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis
The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients w...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412293/ https://www.ncbi.nlm.nih.gov/pubmed/28346382 http://dx.doi.org/10.3390/ijms18040707 |
_version_ | 1783232965918064640 |
---|---|
author | Tomik, Jerzy Tomik, Barbara Gajec, Sebastian Ceranowicz, Piotr Pihut, Małgorzata Olszanecki, Rafał Stręk, Paweł Składzień, Jacek |
author_facet | Tomik, Jerzy Tomik, Barbara Gajec, Sebastian Ceranowicz, Piotr Pihut, Małgorzata Olszanecki, Rafał Stręk, Paweł Składzień, Jacek |
author_sort | Tomik, Jerzy |
collection | PubMed |
description | The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients with ALS were evaluated with manometric examinations of the oral and pharyngeal part of the gastrointestinal tract. Tests were carried out by using the oesophageal balloon-based method with four balloon transducers located 5 cm away from each other. The following manometric parameters were analysed: the base of tongue contraction (BTC) and the upper oesophageal sphincter pressure (UESP), and the hypopharyngeal suction pump (HSP) as well as the oro-pharyngeal, pharyngeal and hypopharyngeal transit time and average pharyngeal bolus velocity (oropharyngeal transit time (OTT), pharyngeal transit time (PTT), hypopharyngeal transit time (HTT) and average pharyngeal bolus velocity (APBV), respectively). Manomatric examinations during swallowing in patients with ALS showed significant weakness of BTC, a decrease of HSP and a decrease of the velocity of bolus transit inside the pharynx which were particularly marked between the first and the third examination. Manometric examinations of the oro-pharyngeal part of the gastrointestinal tract are useful and supportive methods in the analysis of swallowing disturbances in ALS patients. |
format | Online Article Text |
id | pubmed-5412293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-54122932017-05-05 The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis Tomik, Jerzy Tomik, Barbara Gajec, Sebastian Ceranowicz, Piotr Pihut, Małgorzata Olszanecki, Rafał Stręk, Paweł Składzień, Jacek Int J Mol Sci Article The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients with ALS were evaluated with manometric examinations of the oral and pharyngeal part of the gastrointestinal tract. Tests were carried out by using the oesophageal balloon-based method with four balloon transducers located 5 cm away from each other. The following manometric parameters were analysed: the base of tongue contraction (BTC) and the upper oesophageal sphincter pressure (UESP), and the hypopharyngeal suction pump (HSP) as well as the oro-pharyngeal, pharyngeal and hypopharyngeal transit time and average pharyngeal bolus velocity (oropharyngeal transit time (OTT), pharyngeal transit time (PTT), hypopharyngeal transit time (HTT) and average pharyngeal bolus velocity (APBV), respectively). Manomatric examinations during swallowing in patients with ALS showed significant weakness of BTC, a decrease of HSP and a decrease of the velocity of bolus transit inside the pharynx which were particularly marked between the first and the third examination. Manometric examinations of the oro-pharyngeal part of the gastrointestinal tract are useful and supportive methods in the analysis of swallowing disturbances in ALS patients. MDPI 2017-03-27 /pmc/articles/PMC5412293/ /pubmed/28346382 http://dx.doi.org/10.3390/ijms18040707 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Tomik, Jerzy Tomik, Barbara Gajec, Sebastian Ceranowicz, Piotr Pihut, Małgorzata Olszanecki, Rafał Stręk, Paweł Składzień, Jacek The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis |
title | The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis |
title_full | The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis |
title_fullStr | The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis |
title_full_unstemmed | The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis |
title_short | The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis |
title_sort | balloon-based manometry evaluation of swallowing in patients with amyotrophic lateral sclerosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412293/ https://www.ncbi.nlm.nih.gov/pubmed/28346382 http://dx.doi.org/10.3390/ijms18040707 |
work_keys_str_mv | AT tomikjerzy theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT tomikbarbara theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT gajecsebastian theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT ceranowiczpiotr theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT pihutmałgorzata theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT olszaneckirafał theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT strekpaweł theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT składzienjacek theballoonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT tomikjerzy balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT tomikbarbara balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT gajecsebastian balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT ceranowiczpiotr balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT pihutmałgorzata balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT olszaneckirafał balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT strekpaweł balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis AT składzienjacek balloonbasedmanometryevaluationofswallowinginpatientswithamyotrophiclateralsclerosis |