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SCF/C-Kit/JNK/AP-1 Signaling Pathway Promotes Claudin-3 Expression in Colonic Epithelium and Colorectal Carcinoma

Claudin-3 is a major protein of tight junctions (TJs) in the intestinal epithelium and is critical for maintaining cell-cell adhesion, barrier function, and epithelium polarity. Recent studies have shown high claudin-3 levels in several solid tumors, but the regulation mechanism of claudin-3 express...

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Detalles Bibliográficos
Autores principales: Wang, Yaxi, Sun, Tingyi, Sun, Haimei, Yang, Shu, Li, Dandan, Zhou, Deshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412349/
https://www.ncbi.nlm.nih.gov/pubmed/28383479
http://dx.doi.org/10.3390/ijms18040765