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Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice

Colorectal cancer is a common cancer worldwide. Carbonic anhydrase (CA) catalyzes the reversible conversion of carbon dioxide to bicarbonate ion and a proton, and its inhibitor is reported to reduce cancer cell proliferation and induce apoptosis. Therefore, we asked whether acetazolamide, a CA inhib...

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Detalles Bibliográficos
Autores principales: Noma, Nobuharu, Fujii, Gen, Miyamoto, Shingo, Komiya, Masami, Nakanishi, Ruri, Shimura, Misato, Tanuma, Sei-ichi, Mutoh, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412435/
https://www.ncbi.nlm.nih.gov/pubmed/28420165
http://dx.doi.org/10.3390/ijms18040851

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