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E2/ER β Enhances Calcineurin Protein Degradation and PI3K/Akt/MDM2 Signal Transduction to Inhibit ISO-Induced Myocardial Cell Apoptosis

Secretion of multifunctional estrogen and its receptor has been widely considered as the reason for markedly higher frequency of heart disease in men than in women. 17β-Estradiol (E2), for instance, has been reported to prevent development of cardiac apoptosis via activation of estrogen receptors (E...

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Detalles Bibliográficos
Autores principales:	Lin, Kuan-Ho, Kuo, Wei-Wen, Shibu, Marthandam Asokan, Day, Cecilia-Hsuan, Hsieh, You-Liang, Chung, Li-Chin, Chen, Ray-Jade, Wen, Su-Ying, Viswanadha, Vijaya Padma, Huang, Chih-Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412471/ https://www.ncbi.nlm.nih.gov/pubmed/28441761 http://dx.doi.org/10.3390/ijms18040892

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