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Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease

BACKGROUND: Gastroesophageal reflux disease (GERD) is a chronic disease with a negative impact on the quality of life. The aim of this study was to investigate the reflux symptoms and the health-related quality of life in a population with GERD. METHODS: Data from patients with GERD, according to th...

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Autores principales: Lee, Shou-Wu, Lee, Teng-Yu, Lien, Han-Chung, Peng, Yen-Chun, Yeh, Hong-Jeh, Chang, Chi-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412539/
https://www.ncbi.nlm.nih.gov/pubmed/28496527
http://dx.doi.org/10.14740/gr753w
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author Lee, Shou-Wu
Lee, Teng-Yu
Lien, Han-Chung
Peng, Yen-Chun
Yeh, Hong-Jeh
Chang, Chi-Sen
author_facet Lee, Shou-Wu
Lee, Teng-Yu
Lien, Han-Chung
Peng, Yen-Chun
Yeh, Hong-Jeh
Chang, Chi-Sen
author_sort Lee, Shou-Wu
collection PubMed
description BACKGROUND: Gastroesophageal reflux disease (GERD) is a chronic disease with a negative impact on the quality of life. The aim of this study was to investigate the reflux symptoms and the health-related quality of life in a population with GERD. METHODS: Data from patients with GERD, according to the Montreal definition, were collected between January and December 2009. The enrolled patients were classified by different reflux symptoms according to the modified Chinese GERDQ. The general demographic data, the modified GERD impact scores and the SF-36 questionnaire scores of these groups of patients were analyzed. RESULTS: A total of 173 patients were enrolled, and the general data, endoscopic findings and lifestyle habits of the participants with different severity of heartburn or regurgitation were all similar. The patients with moderate severity of reflux symptoms had significant lower SF-36 scores than those with mild severity. The cases with advanced heartburn severity owned the lowest scores among all cases. The impact on the daily activity of each affected individual had a positive association with the stronger severity of reflux symptom. CONCLUSION: The life quality of a population with GERD achieved the meaningful declination in participants with the moderate severity of heartburn or regurgitation. The severity of the reflux symptoms had a greater impact on the normal daily activity of the patients with GERD. The cases with advanced severity of heartburn had the worst well-being.
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spelling pubmed-54125392017-05-11 Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease Lee, Shou-Wu Lee, Teng-Yu Lien, Han-Chung Peng, Yen-Chun Yeh, Hong-Jeh Chang, Chi-Sen Gastroenterology Res Original Article BACKGROUND: Gastroesophageal reflux disease (GERD) is a chronic disease with a negative impact on the quality of life. The aim of this study was to investigate the reflux symptoms and the health-related quality of life in a population with GERD. METHODS: Data from patients with GERD, according to the Montreal definition, were collected between January and December 2009. The enrolled patients were classified by different reflux symptoms according to the modified Chinese GERDQ. The general demographic data, the modified GERD impact scores and the SF-36 questionnaire scores of these groups of patients were analyzed. RESULTS: A total of 173 patients were enrolled, and the general data, endoscopic findings and lifestyle habits of the participants with different severity of heartburn or regurgitation were all similar. The patients with moderate severity of reflux symptoms had significant lower SF-36 scores than those with mild severity. The cases with advanced heartburn severity owned the lowest scores among all cases. The impact on the daily activity of each affected individual had a positive association with the stronger severity of reflux symptom. CONCLUSION: The life quality of a population with GERD achieved the meaningful declination in participants with the moderate severity of heartburn or regurgitation. The severity of the reflux symptoms had a greater impact on the normal daily activity of the patients with GERD. The cases with advanced severity of heartburn had the worst well-being. Elmer Press 2017-04 2017-04-19 /pmc/articles/PMC5412539/ /pubmed/28496527 http://dx.doi.org/10.14740/gr753w Text en Copyright 2017, Lee et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Shou-Wu
Lee, Teng-Yu
Lien, Han-Chung
Peng, Yen-Chun
Yeh, Hong-Jeh
Chang, Chi-Sen
Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease
title Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease
title_full Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease
title_fullStr Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease
title_full_unstemmed Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease
title_short Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease
title_sort correlation between symptom severity and health-related life quality of a population with gastroesophageal reflux disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412539/
https://www.ncbi.nlm.nih.gov/pubmed/28496527
http://dx.doi.org/10.14740/gr753w
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