Centrosome and spindle assembly checkpoint loss leads to neural apoptosis and reduced brain size

Accurate mitotic spindle assembly is critical for mitotic fidelity and organismal development. Multiple processes coordinate spindle assembly and chromosome segregation. Two key components are centrosomes and the spindle assembly checkpoint (SAC), and mutations affecting either can cause human micro...

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Detalles Bibliográficos
Autores principales: Poulton, John S., Cuningham, John C., Peifer, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412557/
https://www.ncbi.nlm.nih.gov/pubmed/28351851
http://dx.doi.org/10.1083/jcb.201607022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412557/
https://www.ncbi.nlm.nih.gov/pubmed/28351851
http://dx.doi.org/10.1083/jcb.201607022

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