Cargando…

Centrosome and spindle assembly checkpoint loss leads to neural apoptosis and reduced brain size

Accurate mitotic spindle assembly is critical for mitotic fidelity and organismal development. Multiple processes coordinate spindle assembly and chromosome segregation. Two key components are centrosomes and the spindle assembly checkpoint (SAC), and mutations affecting either can cause human micro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poulton, John S., Cuningham, John C., Peifer, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412557/ https://www.ncbi.nlm.nih.gov/pubmed/28351851 http://dx.doi.org/10.1083/jcb.201607022

Ejemplares similares

Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function
por: Lerit, Dorothy A., et al.
Publicado: (2015)

Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
por: Diril, M. Kasim, et al.
Publicado: (2016)

Spindle Assembly and Mitosis without Centrosomes in Parthenogenetic Sciara Embryos
por: de Saint Phalle, Brigitte, et al.
Publicado: (1998)

The impact of chromosomes and centrosomes on spindle assembly as observed in living cells
Publicado: (1995)

No stretch for spindle assembly checkpoint
por: Robinson, Richard
Publicado: (2008)

The spindle assembly checkpoint and speciation
por: Jackson, Robert C., et al.
Publicado: (2020)

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly
por: Ohta, Shinya, et al.
Publicado: (2015)

Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes
por: Schneider, Isabell, et al.
Publicado: (2021)

Noise resistance in the spindle assembly checkpoint
por: Doncic, Andreas, et al.
Publicado: (2006)

Reverse Engineering of the Spindle Assembly Checkpoint
por: Doncic, Andreas, et al.
Publicado: (2009)

Spindle assembly checkpoint: the third decade
por: Musacchio, Andrea
Publicado: (2011)

Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly
por: Toso, Alberto, et al.
Publicado: (2009)

Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression
por: Plessner, Matthias, et al.
Publicado: (2019)

Bir1 Deletion Causes Malfunction of the Spindle Assembly Checkpoint and Apoptosis in Yeast
por: Ren, Qun, et al.
Publicado: (2012)

Mapping Mitotic Death: Functional Integration of Mitochondria, Spindle Assembly Checkpoint and Apoptosis
por: Ruan, Weimei, et al.
Publicado: (2019)

Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors
por: Damiani, Devid, et al.
Publicado: (2016)

Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis
por: Reverte, Carlos G., et al.
Publicado: (2006)

Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization
por: Heald, Rebecca, et al.
Publicado: (1997)

Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry
por: Bärenz, Felix, et al.
Publicado: (2018)

The spindle assembly checkpoint gets a complex
por: Dove, Alan W.
Publicado: (2001)

In-Silico Modeling of the Mitotic Spindle Assembly Checkpoint
por: Ibrahim, Bashar, et al.
Publicado: (2008)

Releasing the spindle assembly checkpoint without tension
por: McEwen, Bruce F., et al.
Publicado: (2009)

Kinetochore stretching inactivates the spindle assembly checkpoint
por: Uchida, Kazuhiko S.K., et al.
Publicado: (2009)

Deficient Spindle Assembly Checkpoint in Multiple Myeloma
por: Díaz-Rodríguez, Elena, et al.
Publicado: (2011)

Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint
por: Mossaid, Ikram, et al.
Publicado: (2015)

Regulation of mitotic progression by the spindle assembly checkpoint
por: Lischetti, Tiziana, et al.
Publicado: (2015)

Spindle assembly checkpoint activation and silencing at kinetochores
por: Lara-Gonzalez, Pablo, et al.
Publicado: (2021)

Loss of spindle assembly checkpoint–mediated inhibition of Cdc20 promotes tumorigenesis in mice
por: Li, Min, et al.
Publicado: (2009)

Loss of spindle assembly checkpoint–mediated inhibition of Cdc20 promotes tumorigenesis in mice
por: Li, Min, et al.
Publicado: (2009)

Loss of centromeric RNA activates the spindle assembly checkpoint in mammalian female meiosis I
por: Wu, Tianyu, et al.
Publicado: (2021)

Induction of Spindle Multipolarity by Centrosomal Cluster Inhibition
por: Krämer, Alwin, et al.
Publicado: (2008)

Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic
por: Henriques, Ana C., et al.
Publicado: (2021)

A quantitative systems view of the spindle assembly checkpoint
por: Ciliberto, Andrea, et al.
Publicado: (2009)

An Overview of the Spindle Assembly Checkpoint Status in Oral Cancer
por: Teixeira, José Henrique, et al.
Publicado: (2014)

Sustaining the spindle assembly checkpoint to improve cancer therapy
por: Visconti, Roberta, et al.
Publicado: (2015)

Spindle Assembly Checkpoint Acquisition at the Mid-Blastula Transition
por: Zhang, Maomao, et al.
Publicado: (2015)

Multiple Duties for Spindle Assembly Checkpoint Kinases in Meiosis
por: Marston, Adele L., et al.
Publicado: (2017)

Silencing the spindle assembly checkpoint: Let’s play Polo!
por: Benzi, Giorgia, et al.
Publicado: (2020)

A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes
por: Gryaznova, Yuliya, et al.
Publicado: (2016)

Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion
por: Silva, Rui D., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_130j4h5ge31buatg0ps0j8eeus