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Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression

Epithelial–mesenchymal transitions play key roles in development and cancer and entail the loss of epithelial polarity and cell adhesion. In this study, we use quantitative live imaging of ingressing neuroblasts (NBs) in Drosophila melanogaster embryos to assess apical domain loss and junctional dis...

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Detalles Bibliográficos
Autores principales: Simões, Sérgio, Oh, Youjin, Wang, Michael F.Z., Fernandez-Gonzalez, Rodrigo, Tepass, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412560/
https://www.ncbi.nlm.nih.gov/pubmed/28363972
http://dx.doi.org/10.1083/jcb.201608038