Cargando…

The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death

The linear ubiquitin chain assembly complex (LUBAC) is the only known E3 ubiquitin ligase which catalyses the generation of linear ubiquitin linkages de novo. LUBAC is a crucial component of various immune receptor signalling pathways. Here, we show that LUBAC forms part of the TRAIL‐R‐associated co...

Descripción completa

Detalles Bibliográficos
Autores principales: Lafont, Elodie, Kantari‐Mimoun, Chahrazade, Draber, Peter, De Miguel, Diego, Hartwig, Torsten, Reichert, Matthias, Kupka, Sebastian, Shimizu, Yutaka, Taraborrelli, Lucia, Spit, Maureen, Sprick, Martin R, Walczak, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412822/
https://www.ncbi.nlm.nih.gov/pubmed/28258062
http://dx.doi.org/10.15252/embj.201695699