Cargando…
Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial
Pathologically elevated immune activation and inflammation contribute to HIV disease progression and immunodeficiency, potentially mediated by elevated levels of prostaglandin E(2), which suppress HIV-specific T cell responses. We have previously shown that a high dose of the cyclooxygenase-2 inhibi...
Autores principales: | Prebensen, Christian, Trøseid, Marius, Ueland, Thor, Dahm, Anders, Sandset, Per Morten, Aaberge, Ingeborg, Waalen, Kristian, Dyrhol-Riise, Anne Ma, Taskén, Kjetil, Kvale, Dag |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413033/ https://www.ncbi.nlm.nih.gov/pubmed/28464042 http://dx.doi.org/10.1371/journal.pone.0176527 |
Ejemplares similares
-
Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors
por: Lieske, Nora V., et al.
Publicado: (2015) -
Regulation of Gag- and Env-Specific CD8(+) T Cell Responses in ART-Naïve HIV-Infected Patients: Potential Implications for Individualized Immunotherapy
por: Prebensen, Christian, et al.
Publicado: (2016) -
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4(+) recovery
por: Stiksrud, Birgitte, et al.
Publicado: (2019) -
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection
por: Tonby, Kristian, et al.
Publicado: (2016) -
Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
por: Jøntvedt Jørgensen, Marthe, et al.
Publicado: (2021)