TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects

The spores of pathogenic bacteria are involved in host entry and the initial encounter with the host immune system. How bacterial spores interact with host immunity, however, remains poorly understood. Here, we show that the spores of Bacillus anthracis (BA), the etiologic agent of anthrax, possess...

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Detalles Bibliográficos
Autores principales: Choo, Min-Kyung, Sano, Yasuyo, Kim, Changhoon, Yasuda, Kei, Li, Xiao-Dong, Lin, Xin, Stenzel-Poore, Mary, Alexopoulou, Lena, Ghosh, Sankar, Latz, Eicke, Rifkin, Ian R., Chen, Zhijian J., Stewart, George C., Chong, Hyonyong, Park, Jin Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413331/
https://www.ncbi.nlm.nih.gov/pubmed/28400473
http://dx.doi.org/10.1084/jem.20161141

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