Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

Neutrophils have crucial antimicrobial functions but are also thought to contribute to tissue injury upon exposure to bacterial products, such as lipopolysaccharide (LPS). To study the role of neutrophils in LPS-induced endotoxemia, we developed a new mouse model, PMN(DTR) mice, in which injection o...

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Detalles Bibliográficos
Autores principales: Reber, Laurent L., Gillis, Caitlin M., Starkl, Philipp, Jönsson, Friederike, Sibilano, Riccardo, Marichal, Thomas, Gaudenzio, Nicolas, Bérard, Marion, Rogalla, Stephan, Contag, Christopher H., Bruhns, Pierre, Galli, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413333/
https://www.ncbi.nlm.nih.gov/pubmed/28385925
http://dx.doi.org/10.1084/jem.20161238

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