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Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide
Neutrophils have crucial antimicrobial functions but are also thought to contribute to tissue injury upon exposure to bacterial products, such as lipopolysaccharide (LPS). To study the role of neutrophils in LPS-induced endotoxemia, we developed a new mouse model, PMN(DTR) mice, in which injection o...
Autores principales: | Reber, Laurent L., Gillis, Caitlin M., Starkl, Philipp, Jönsson, Friederike, Sibilano, Riccardo, Marichal, Thomas, Gaudenzio, Nicolas, Bérard, Marion, Rogalla, Stephan, Contag, Christopher H., Bruhns, Pierre, Galli, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413333/ https://www.ncbi.nlm.nih.gov/pubmed/28385925 http://dx.doi.org/10.1084/jem.20161238 |
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