The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity

Dendritic cells (DCs) are crucial for mediating immune responses but, when deregulated, also contribute to immunological disorders, such as autoimmunity. The molecular mechanism underlying the function of DCs is incompletely understood. In this study, we have identified TANK-binding kinase 1 (TBK1),...

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Detalles Bibliográficos
Autores principales: Xiao, Yichuan, Zou, Qiang, Xie, Xiaoping, Liu, Ting, Li, Haiyan S., Jie, Zuliang, Jin, Jin, Hu, Hongbo, Manyam, Ganiraju, Zhang, Li, Cheng, Xuhong, Wang, Hui, Marie, Isabelle, Levy, David E., Watowich, Stephanie S., Sun, Shao-Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413337/
https://www.ncbi.nlm.nih.gov/pubmed/28356390
http://dx.doi.org/10.1084/jem.20161524

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