Cargando…
Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2
Synaptic cell adhesion molecules represent important targets for neuronal activity-dependent proteolysis. Postsynaptic neuroligins (NLs) form trans-synaptic complexes with presynaptic neurexins (NXs). Both NXs and NLs are cleaved from the cell surface by metalloproteases in an activity-dependent man...
Autores principales: | Gjørlund, Michelle D., Carlsen, Eva M. M., Kønig, Andreas B., Dmytrieva, Oksana, Petersen, Anders V., Jacobsen, Jacob, Berezin, Vladimir, Perrier, Jean-François, Owczarek, Sylwia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413576/ https://www.ncbi.nlm.nih.gov/pubmed/28515678 http://dx.doi.org/10.3389/fnmol.2017.00116 |
Ejemplares similares
-
A neuroligin-1-derived peptide stimulates phosphorylation of the NMDA receptor NR1 subunit and rescues MK-801-induced decrease in long-term potentiation and memory impairment
por: Korshunova, Irina, et al.
Publicado: (2015) -
The soluble neurexin-1β ectodomain causes calcium influx and augments dendritic outgrowth and synaptic transmission
por: Wierda, Keimpe D. B., et al.
Publicado: (2020) -
Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 “Signalosome”
por: Owczarek, Sylwia, et al.
Publicado: (2015) -
The Interplay between Synaptic Activity and Neuroligin Function in the CNS
por: Hu, Xiaoge, et al.
Publicado: (2015) -
Constitutive activity of metabotropic glutamate receptor 7
por: Kammermeier, Paul J
Publicado: (2015)