Cargando…
Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease
Immune checkpoint molecules function as a system of checks and balances that enhance or inhibit immune responses to infectious agents, foreign tissues, and cancerous cells. Immunotherapies that target immune checkpoint molecules, particularly the inhibitory molecules programmed cell death 1 and cyto...
Autores principales: | Flies, Andrew S., Blackburn, Nicholas B., Lyons, Alan Bruce, Hayball, John D., Woods, Gregory M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413580/ https://www.ncbi.nlm.nih.gov/pubmed/28515726 http://dx.doi.org/10.3389/fimmu.2017.00513 |
Ejemplares similares
-
PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-γ and Can Be Expressed in the Tumor Microenvironment
por: Flies, Andrew S., et al.
Publicado: (2016) -
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours
por: Ong, Chrissie E. B., et al.
Publicado: (2022) -
Demonstration of immune responses against devil facial tumour disease in wild Tasmanian devils
por: Pye, Ruth, et al.
Publicado: (2016) -
Inducible IFN-γ Expression for MHC-I Upregulation in Devil Facial Tumor Cells
por: Ong, Chrissie E. B., et al.
Publicado: (2019) -
Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release
por: Pye, Ruth, et al.
Publicado: (2018)