Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies

The majority of breast cancer models for drug discovery are based on orthotopic or subcutaneous tumours. Therapeutic responses of metastases, especially microscopic metastases, are likely to differ from these tumours due to distinct cancer-microenvironment crosstalk in distant organs. Here, to recap...

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Detalles Bibliográficos
Autores principales: Wang, Hai, Tian, Lin, Goldstein, Amit, Liu, Jun, Lo, Hin-Ching, Sheng, Kuanwei, Welte, Thomas, Wong, Stephen T.C., Gugala, Zbigniew, Stossi, Fabio, Zong, Chenghang, Li, Zonghai, Mancini, Michael A., Zhang, Xiang H.-F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413944/
https://www.ncbi.nlm.nih.gov/pubmed/28429794
http://dx.doi.org/10.1038/ncomms15045

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