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Transiently antigen-primed B cells return to naive-like state in absence of T-cell help

The perspective that naive B-cell recognition of antigen in the absence of T-cell help causes cell death or anergy is supported by in vivo studies of B cells that are continuously exposed to self-antigens. However, intravital imaging suggests that early B-cell recognition of large foreign antigens m...

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Detalles Bibliográficos
Autores principales: Turner, Jackson S., Marthi, Matangi, Benet, Zachary L., Grigorova, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413946/
https://www.ncbi.nlm.nih.gov/pubmed/28429719
http://dx.doi.org/10.1038/ncomms15072