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Direct comparison of distinct naive pluripotent states in human embryonic stem cells

Until recently, human embryonic stem cells (hESCs) were shown to exist in a state of primed pluripotency, while mouse embryonic stem cells (mESCs) display a naive or primed pluripotent state. Here we show the rapid conversion of in-house-derived primed hESCs on mouse embryonic feeder layer (MEF) to...

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Detalles Bibliográficos
Autores principales: Warrier, S., Van der Jeught, M., Duggal, G., Tilleman, L., Sutherland, E., Taelman, J., Popovic, M., Lierman, S., Chuva De Sousa Lopes, S., Van Soom, A., Peelman, L., Van Nieuwerburgh, F., De Coninck, D. I. M., Menten, B., Mestdagh, P., Van de Sompele, J., Deforce, D., De Sutter, P., Heindryckx, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413953/
https://www.ncbi.nlm.nih.gov/pubmed/28429706
http://dx.doi.org/10.1038/ncomms15055

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