A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory

Increasing age is tightly linked to decreased thickness of the human neocortex. The biological mechanisms that mediate this effect are hitherto unknown. The DNA methylome, as part of the epigenome, contributes significantly to age-related phenotypic changes. Here, we identify an epigenetic signature...

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Detalles Bibliográficos
Autores principales: Freytag, Virginie, Carrillo-Roa, Tania, Milnik, Annette, Sämann, Philipp G., Vukojevic, Vanja, Coynel, David, Demougin, Philippe, Egli, Tobias, Gschwind, Leo, Jessen, Frank, Loos, Eva, Maier, Wolfgang, Riedel-Heller, Steffi G., Scherer, Martin, Vogler, Christian, Wagner, Michael, Binder, Elisabeth B., de Quervain, Dominique J. -F., Papassotiropoulos, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414038/
https://www.ncbi.nlm.nih.gov/pubmed/28443631
http://dx.doi.org/10.1038/ncomms15193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414038/
https://www.ncbi.nlm.nih.gov/pubmed/28443631
http://dx.doi.org/10.1038/ncomms15193

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