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A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory
Increasing age is tightly linked to decreased thickness of the human neocortex. The biological mechanisms that mediate this effect are hitherto unknown. The DNA methylome, as part of the epigenome, contributes significantly to age-related phenotypic changes. Here, we identify an epigenetic signature...
Autores principales: | Freytag, Virginie, Carrillo-Roa, Tania, Milnik, Annette, Sämann, Philipp G., Vukojevic, Vanja, Coynel, David, Demougin, Philippe, Egli, Tobias, Gschwind, Leo, Jessen, Frank, Loos, Eva, Maier, Wolfgang, Riedel-Heller, Steffi G., Scherer, Martin, Vogler, Christian, Wagner, Michael, Binder, Elisabeth B., de Quervain, Dominique J. -F., Papassotiropoulos, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414038/ https://www.ncbi.nlm.nih.gov/pubmed/28443631 http://dx.doi.org/10.1038/ncomms15193 |
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