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Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis
Chlamydia trachomatis remains a leading cause of bacterial sexually transmitted infections and preventable blindness worldwide. There are, however, limited in vitro models to study the role of host genetics in the response of macrophages to this obligate human pathogen. Here, we describe an approach...
Autores principales: | Yeung, Amy T. Y., Hale, Christine, Lee, Amy H., Gill, Erin E., Bushell, Wendy, Parry-Smith, David, Goulding, David, Pickard, Derek, Roumeliotis, Theodoros, Choudhary, Jyoti, Thomson, Nick, Skarnes, William C., Dougan, Gordon, Hancock, Robert E. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414054/ https://www.ncbi.nlm.nih.gov/pubmed/28440293 http://dx.doi.org/10.1038/ncomms15013 |
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