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KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling

Human colorectal cancer stem cells (CSCs) are tumour initiating cells that can self-renew and are highly tumorigenic and chemoresistant. While genetic mutations associated with human colorectal cancer development are well-known, little is known about how and whether epigenetic factors specifically c...

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Detalles Bibliográficos
Autores principales:	Li, Jiong, Yu, Bo, Deng, Peng, Cheng, Yingduan, Yu, Yongxin, Kevork, Kareena, Ramadoss, Sivakumar, Ding, Xiangming, Li, Xinmin, Wang, Cun-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414094/ https://www.ncbi.nlm.nih.gov/pubmed/28440295 http://dx.doi.org/10.1038/ncomms15146

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