Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report

Voriconazole, a broad-spectrum antifungal, has been associated with visual and auditory hallucinations. We report the case of patient being treated with voriconazole for pulmonary aspergillosis who developed visual hallucinations and new suicidal ideation with plan. Voriconazole troughs were suprath...

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Detalles Bibliográficos
Autores principales: Jansen, Jeffrey W., Sen, Sumon K., Moenster, Ryan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
ID Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414099/
https://www.ncbi.nlm.nih.gov/pubmed/28480228
http://dx.doi.org/10.1093/ofid/ofw215
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author Jansen, Jeffrey W.
Sen, Sumon K.
Moenster, Ryan P.
author_facet Jansen, Jeffrey W.
Sen, Sumon K.
Moenster, Ryan P.
author_sort Jansen, Jeffrey W.
collection PubMed
description Voriconazole, a broad-spectrum antifungal, has been associated with visual and auditory hallucinations. We report the case of patient being treated with voriconazole for pulmonary aspergillosis who developed visual hallucinations and new suicidal ideation with plan. Voriconazole troughs were supratherapeutic (9.0 mcg/mL) and the patient was positive for the CYP2C19*1/*2 allele.
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spelling pubmed-54140992017-05-05 Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report Jansen, Jeffrey W. Sen, Sumon K. Moenster, Ryan P. Open Forum Infect Dis ID Case Voriconazole, a broad-spectrum antifungal, has been associated with visual and auditory hallucinations. We report the case of patient being treated with voriconazole for pulmonary aspergillosis who developed visual hallucinations and new suicidal ideation with plan. Voriconazole troughs were supratherapeutic (9.0 mcg/mL) and the patient was positive for the CYP2C19*1/*2 allele. Oxford University Press 2017-01-19 /pmc/articles/PMC5414099/ /pubmed/28480228 http://dx.doi.org/10.1093/ofid/ofw215 Text en © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle ID Case
Jansen, Jeffrey W.
Sen, Sumon K.
Moenster, Ryan P.
Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report
title Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report
title_full Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report
title_fullStr Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report
title_full_unstemmed Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report
title_short Elevated Voriconazole Level Associated With Hallucinations and Suicidal Ideation: A Case Report
title_sort elevated voriconazole level associated with hallucinations and suicidal ideation: a case report
topic ID Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414099/
https://www.ncbi.nlm.nih.gov/pubmed/28480228
http://dx.doi.org/10.1093/ofid/ofw215
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