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The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling
BACKGROUND: Renal cell carcinomas (RCCs) display broad resistance against conventional radio- and chemotherapies, which is due at least in part to impairments in both extrinsic and intrinsic apoptotic pathways. One important anti-apoptotic factor that is strongly overexpressed in RCCs and known to i...
Autores principales: | Toth, Csaba, Funke, Sarah, Nitsche, Vanessa, Liverts, Anna, Zlachevska, Viktoriya, Gasis, Marcia, Wiek, Constanze, Hanenberg, Helmut, Mahotka, Csaba, Schirmacher, Peter, Heikaus, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414156/ https://www.ncbi.nlm.nih.gov/pubmed/28464919 http://dx.doi.org/10.1186/s12964-017-0170-5 |
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