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Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

BACKGROUND: Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadotropin in...

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Detalles Bibliográficos
Autores principales:	Han, Xinghui, He, Yuanyuan, Zeng, Gulan, Wang, Yonghong, Sun, Wen, Liu, Junchao, Sun, Yanyan, Yu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414188/ https://www.ncbi.nlm.nih.gov/pubmed/28464910 http://dx.doi.org/10.1186/s12958-017-0254-5

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