A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination

Schwann cell (SC) myelination in the peripheral nervous system is essential for motor function, and uncontrolled SC proliferation occurs in cancer. Here, we show that a dual role for Hippo effectors TAZ and YAP in SC proliferation and myelination through modulating G-protein expression and interacti...

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Detalles Bibliográficos
Autores principales: Deng, Yaqi, Wu, Lai Man Natalie, Bai, Shujun, Zhao, Chuntao, Wang, Haibo, Wang, Jincheng, Xu, Lingli, Sakabe, Masahide, Zhou, Wenhao, Xin, Mei, Lu, Q. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414202/
https://www.ncbi.nlm.nih.gov/pubmed/28443644
http://dx.doi.org/10.1038/ncomms15161

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