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New leads for fragment-based design of rhenium/technetium radiopharmaceutical agents
Multiple possibilities for the coordination of fac-[Re(CO)(3)(H(2)O)(3)](+) to a protein have been determined and include binding to Asp, Glu, Arg and His amino-acid residues as well as to the C-terminal carboxylate in the vicinity of Leu and Pro. The large number of rhenium metal complex binding si...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414402/ https://www.ncbi.nlm.nih.gov/pubmed/28512575 http://dx.doi.org/10.1107/S2052252517003475 |