Primary Villoglandular Mucinous Adenocarcinoma of the Vulva

Primary villoglandular mucinous adenocarcinoma of the vulva is rare tumor. We report a case of 68-year-old woman who developed this very uncommon malignant tumor. Immunohistochemical examination of this tumor revealed positive staining for Cytokeratin 20, Mucin 2, and CDX2, although Cytokeratin 7 an...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuzaki, Akiko, Saio, Masanao, Kosuge, Noritake, Aoyama, Hajime, Tamaki, Tomoko, Matsumoto, Hirofumi, Yoshimi, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414496/
https://www.ncbi.nlm.nih.gov/pubmed/28503335
http://dx.doi.org/10.1155/2017/1765460
_version_ 1783233388788842496
author Matsuzaki, Akiko
Saio, Masanao
Kosuge, Noritake
Aoyama, Hajime
Tamaki, Tomoko
Matsumoto, Hirofumi
Yoshimi, Naoki
author_facet Matsuzaki, Akiko
Saio, Masanao
Kosuge, Noritake
Aoyama, Hajime
Tamaki, Tomoko
Matsumoto, Hirofumi
Yoshimi, Naoki
author_sort Matsuzaki, Akiko
collection PubMed
description Primary villoglandular mucinous adenocarcinoma of the vulva is rare tumor. We report a case of 68-year-old woman who developed this very uncommon malignant tumor. Immunohistochemical examination of this tumor revealed positive staining for Cytokeratin 20, Mucin 2, and CDX2, although Cytokeratin 7 and Mucin 6 were negative. This positive staining indicated the tumor enteric type characters. In order to exclude the possibility of the metastasis from another site, we thoroughly evaluated clinical data and extensively investigated the whole body. However, we could not detect any other tumors. The patient was treated by tumor resection. The patient remains free of disease 5 years after surgery.
format Online
Article
Text
id pubmed-5414496
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-54144962017-05-14 Primary Villoglandular Mucinous Adenocarcinoma of the Vulva Matsuzaki, Akiko Saio, Masanao Kosuge, Noritake Aoyama, Hajime Tamaki, Tomoko Matsumoto, Hirofumi Yoshimi, Naoki Case Rep Pathol Case Report Primary villoglandular mucinous adenocarcinoma of the vulva is rare tumor. We report a case of 68-year-old woman who developed this very uncommon malignant tumor. Immunohistochemical examination of this tumor revealed positive staining for Cytokeratin 20, Mucin 2, and CDX2, although Cytokeratin 7 and Mucin 6 were negative. This positive staining indicated the tumor enteric type characters. In order to exclude the possibility of the metastasis from another site, we thoroughly evaluated clinical data and extensively investigated the whole body. However, we could not detect any other tumors. The patient was treated by tumor resection. The patient remains free of disease 5 years after surgery. Hindawi 2017 2017-04-19 /pmc/articles/PMC5414496/ /pubmed/28503335 http://dx.doi.org/10.1155/2017/1765460 Text en Copyright © 2017 Akiko Matsuzaki et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Matsuzaki, Akiko
Saio, Masanao
Kosuge, Noritake
Aoyama, Hajime
Tamaki, Tomoko
Matsumoto, Hirofumi
Yoshimi, Naoki
Primary Villoglandular Mucinous Adenocarcinoma of the Vulva
title Primary Villoglandular Mucinous Adenocarcinoma of the Vulva
title_full Primary Villoglandular Mucinous Adenocarcinoma of the Vulva
title_fullStr Primary Villoglandular Mucinous Adenocarcinoma of the Vulva
title_full_unstemmed Primary Villoglandular Mucinous Adenocarcinoma of the Vulva
title_short Primary Villoglandular Mucinous Adenocarcinoma of the Vulva
title_sort primary villoglandular mucinous adenocarcinoma of the vulva
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414496/
https://www.ncbi.nlm.nih.gov/pubmed/28503335
http://dx.doi.org/10.1155/2017/1765460
work_keys_str_mv AT matsuzakiakiko primaryvilloglandularmucinousadenocarcinomaofthevulva
AT saiomasanao primaryvilloglandularmucinousadenocarcinomaofthevulva
AT kosugenoritake primaryvilloglandularmucinousadenocarcinomaofthevulva
AT aoyamahajime primaryvilloglandularmucinousadenocarcinomaofthevulva
AT tamakitomoko primaryvilloglandularmucinousadenocarcinomaofthevulva
AT matsumotohirofumi primaryvilloglandularmucinousadenocarcinomaofthevulva
AT yoshiminaoki primaryvilloglandularmucinousadenocarcinomaofthevulva

Ejemplares similares