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The effect of Ingenol-B on the suppressive capacity of elite suppressor HIV-specific CD8+ T cells

BACKGROUND: Some latency-reversing agents (LRAs) inhibit HIV-specific CD8+ T cell responses. In a prior study of protein kinase C (PKC) agonists, we found that bryostatin-1 inhibited elite controller/suppressor (ES) CD8+ T cell suppressive activity whereas prostratin had no effect. Ingenol-B is anot...

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Detalles Bibliográficos
Autores principales:	Kwaa, Abena K., Goldsborough, Kennedy, Walker-Sperling, Victoria E., Pianowski, Luiz F., Gama, Lucio, Blankson, Joel N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414940/ https://www.ncbi.nlm.nih.gov/pubmed/28467486 http://dx.doi.org/10.1371/journal.pone.0174516

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