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Anti-cancer stemness and anti-invasive activity of bitter taste receptors, TAS2R8 and TAS2R10, in human neuroblastoma cells

Neuroblastoma (NB) originates from immature neuronal cells and currently has a poor clinical outcome. NB cells possess cancer stem cells (CSCs) characteristics that facilitate the initiation of a tumor, as well as its metastasis. Human bitter taste receptors, referred to as TAS2Rs, are one of five t...

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Detalles Bibliográficos
Autores principales: Seo, Yoona, Kim, Yoo-Sun, Lee, Kyung Eun, Park, Tai Hyun, Kim, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414998/
https://www.ncbi.nlm.nih.gov/pubmed/28467517
http://dx.doi.org/10.1371/journal.pone.0176851