Cargando…

Conditional Depletion of Hippocampal Brain-Derived Neurotrophic Factor Exacerbates Neuropathology in a Mouse Model of Alzheimer’s Disease

Damage occurring to noradrenergic neurons in the locus coeruleus (LC) contributes to the evolution of neuroinflammation and neurodegeneration in a variety of conditions and diseases. One cause of LC damage may be loss of neurotrophic support from LC target regions. We tested this hypothesis by condi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Braun, David J., Kalinin, Sergey, Feinstein, Douglas L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415058/ https://www.ncbi.nlm.nih.gov/pubmed/28266222 http://dx.doi.org/10.1177/1759091417696161

Ejemplares similares

Brain-derived neurotrophic factor interplay with oxidative stress: neuropathology approach in potential biomarker of Alzheimer’s disease
por: Shen, Robert, et al.
Publicado: (2023)

Transcriptional profiles in olfactory pathway–associated brain regions of African green monkeys: Associations with age and Alzheimer's disease neuropathology
por: Negrey, Jacob D., et al.
Publicado: (2022)

Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition
por: Hollands, Carolyn, et al.
Publicado: (2017)

Obese mice exposed to psychosocial stress display cardiac and hippocampal dysfunction associated with local brain-derived neurotrophic factor depletion
por: Agrimi, Jacopo, et al.
Publicado: (2019)

Brain-Derived Neurotrophic Factor Serum Levels and Hippocampal Volume in Mild Cognitive Impairment and Dementia due to Alzheimer Disease
por: Borba, Ericksen Mielle, et al.
Publicado: (2016)

Aquaporins in Brain Edema and Neuropathological Conditions
por: Filippidis, Aristotelis S., et al.
Publicado: (2016)

Microglia in Alzheimer Brain: A Neuropathological Perspective
por: Mrak, Robert E.
Publicado: (2012)

Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus
por: Engel, Tobias, et al.
Publicado: (2018)

Brain-derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential
por: Gao, Lina, et al.
Publicado: (2022)

Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis
por: Karahan, Hande, et al.
Publicado: (2021)

Hippocampal phospho-tau/MAPT neuropathology in the fornix in Alzheimer disease: an immunohistochemical autopsy study
por: Plowey, Edward D., et al.
Publicado: (2016)

Associations between hippocampal morphometry and neuropathologic markers of Alzheimer's disease using 7 T MRI
por: Blanken, Anna E., et al.
Publicado: (2017)

Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons
por: Graves, A. R., et al.
Publicado: (2016)

Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis
por: Xu, Danfeng, et al.
Publicado: (2017)

Hippocampal Volume and Plasma Brain-Derived Neurotrophic Factor Levels in Patients With Depression and Healthy Controls
por: Fujii, Rintaro, et al.
Publicado: (2022)

Edaravone Enhances Brain-Derived Neurotrophic Factor Production in the Ischemic Mouse Brain
por: Okuyama, Satoshi, et al.
Publicado: (2015)

Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice
por: de Sousa, Diana M. Bessa, et al.
Publicado: (2023)

CD8(+) T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy
por: Sutter, Pearl A., et al.
Publicado: (2023)

Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
por: Joseph, Donald J., et al.
Publicado: (2019)

Hippocampal Reduction of α-Synuclein via RNA Interference Improves Neuropathology in Alzheimer’s Disease Mice
por: Leitão, André D.G., et al.
Publicado: (2023)

Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease
por: Fonseca, Maria I, et al.
Publicado: (2011)

Absence of Thyroid Hormone Induced Delayed Dendritic Arborization in Mouse Primary Hippocampal Neurons Through Insufficient Expression of Brain-Derived Neurotrophic Factor
por: Yajima, Hiroyuki, et al.
Publicado: (2021)

Selective Loss of Brain-Derived Neurotrophic Factor Exacerbates Brain Injury by Enhancing Neuroinflammation in Experimental Streptococcus pneumoniae Meningitis
por: Zhao, Shengnan, et al.
Publicado: (2020)

Influence of brain-derived neurotrophic factor on pathfinding of dentate granule cell axons, the hippocampal mossy fibers
por: Tamura, Makoto, et al.
Publicado: (2009)

Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF)
por: Menna, Elisabetta, et al.
Publicado: (2009)

Decreased hippocampal brain‐derived neurotrophic factor and impaired cognitive function by hypoglossal nerve transection in rats
por: Kim, Doyun, et al.
Publicado: (2017)

Signalosomes in the Brain: Relevance in the Development of Certain Neuropathologies Such as Alzheimer's Disease
por: Marin, Raquel
Publicado: (2011)

Depletion of microglia exacerbates postischemic inflammation and brain injury
por: Jin, Wei-Na, et al.
Publicado: (2017)

The neuropathological diagnosis of Alzheimer’s disease
por: DeTure, Michael A., et al.
Publicado: (2019)

Characterizing the Role of Brain Derived Neurotrophic Factor Genetic Variation in Alzheimer’s Disease Neurodegeneration
por: Honea, Robyn A., et al.
Publicado: (2013)

The effect of dietary supplementation on brain-derived neurotrophic factor and cognitive functioning in Alzheimer's dementia
por: Martin, Alicia, et al.
Publicado: (2017)

Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease
por: Jiao, S-S, et al.
Publicado: (2016)

Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease
por: Jaberi, Sama, et al.
Publicado: (2023)

Neurotrophic factors and hippocampal activity in PTSD
por: Tural, Ümit, et al.
Publicado: (2018)

Selective Depletion of CREB in Serotonergic Neurons Affects the Upregulation of Brain-Derived Neurotrophic Factor Evoked by Chronic Fluoxetine Treatment
por: Rafa-Zabłocka, Katarzyna, et al.
Publicado: (2018)

Brain-derived Neurotrophic Factor in Megakaryocytes
por: Chacón-Fernández, Pedro, et al.
Publicado: (2016)

Brain-derived neurotrophic factor and schizophrenia
por: Gören, Jessica L.
Publicado: (2016)

Brain-derived neurotrophic factor as biomarker
por: Sookaromdee, Pathum, et al.
Publicado: (2020)

Brain-Derived Neurotrophic Factor and Diabetes
por: Rozanska, Olga, et al.
Publicado: (2020)

Activity- and Ca(2+)-Dependent Modulation of Surface Expression of Brain-Derived Neurotrophic Factor Receptors in Hippocampal Neurons
por: Du, Jing, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_a0ovbe0vv63kpi7cevh0gdm1g6