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Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia

The antimicrobial properties of essential oil from various Santolina species have not been investigated enough in the previous studies dealing with the biological activities of medicinal plants. In Tunisia, Santolina chamaecyparissus L. (Asteraceae) is the only Santolina species recorded and is used...

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Autores principales: Bel Hadj Salah-Fatnassi, Karima, Hassayoun, Faten, Cheraif, Imed, Khan, Saba, Jannet, Hichem Ben, Hammami, Mohamed, Aouni, Mahjoub, Harzallah-Skhiri, Fethia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415143/
https://www.ncbi.nlm.nih.gov/pubmed/28490960
http://dx.doi.org/10.1016/j.sjbs.2016.03.005
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author Bel Hadj Salah-Fatnassi, Karima
Hassayoun, Faten
Cheraif, Imed
Khan, Saba
Jannet, Hichem Ben
Hammami, Mohamed
Aouni, Mahjoub
Harzallah-Skhiri, Fethia
author_facet Bel Hadj Salah-Fatnassi, Karima
Hassayoun, Faten
Cheraif, Imed
Khan, Saba
Jannet, Hichem Ben
Hammami, Mohamed
Aouni, Mahjoub
Harzallah-Skhiri, Fethia
author_sort Bel Hadj Salah-Fatnassi, Karima
collection PubMed
description The antimicrobial properties of essential oil from various Santolina species have not been investigated enough in the previous studies dealing with the biological activities of medicinal plants. In Tunisia, Santolina chamaecyparissus L. (Asteraceae) is the only Santolina species recorded and is used as vermifuge and emmenagogue. The chemical composition, antibacterial and antifungal properties of essential oils from the flowerheads and roots of spontaneous S. chamaecyparissus growing in Tunisia and the chemical composition which leads to the Tunisian chemotype are investigated here for the first time. Essential oils isolated by hydro distillation from flowerheads and roots of S. chamaecyparissus were analyzed by GC and GC/MS. Two methods served for antimicrobial assays of the essential oils: diffusion in a solid medium and micro-well dilution assay. Antifungal tests were carried out by the agar incorporation method. Sixty-seven constituents were identified from the essential oil of the flowerhead. The major constituents were: 1,8-cineole and β-eudesmol. Two non identified compounds were present at the highest concentration in root oil. Flowerhead oil was characterized by high contents in monoterpenes and sesquiterpenes oxygenated compounds. The flowerhead essential oil demonstrated potent of antibacterial properties against Pseudomonas aeruginosa ATCC and Enterococcus faecalis ATCC, with MIC of 0.625 μg/ml. These findings demonstrate that the flowerhead essential oils of S. chamaecyparissus have excellent antibacterial properties and for this reason they could contribute to decrease the problem of microbial resistance to antibiotics.
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spelling pubmed-54151432017-05-10 Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia Bel Hadj Salah-Fatnassi, Karima Hassayoun, Faten Cheraif, Imed Khan, Saba Jannet, Hichem Ben Hammami, Mohamed Aouni, Mahjoub Harzallah-Skhiri, Fethia Saudi J Biol Sci Original Article The antimicrobial properties of essential oil from various Santolina species have not been investigated enough in the previous studies dealing with the biological activities of medicinal plants. In Tunisia, Santolina chamaecyparissus L. (Asteraceae) is the only Santolina species recorded and is used as vermifuge and emmenagogue. The chemical composition, antibacterial and antifungal properties of essential oils from the flowerheads and roots of spontaneous S. chamaecyparissus growing in Tunisia and the chemical composition which leads to the Tunisian chemotype are investigated here for the first time. Essential oils isolated by hydro distillation from flowerheads and roots of S. chamaecyparissus were analyzed by GC and GC/MS. Two methods served for antimicrobial assays of the essential oils: diffusion in a solid medium and micro-well dilution assay. Antifungal tests were carried out by the agar incorporation method. Sixty-seven constituents were identified from the essential oil of the flowerhead. The major constituents were: 1,8-cineole and β-eudesmol. Two non identified compounds were present at the highest concentration in root oil. Flowerhead oil was characterized by high contents in monoterpenes and sesquiterpenes oxygenated compounds. The flowerhead essential oil demonstrated potent of antibacterial properties against Pseudomonas aeruginosa ATCC and Enterococcus faecalis ATCC, with MIC of 0.625 μg/ml. These findings demonstrate that the flowerhead essential oils of S. chamaecyparissus have excellent antibacterial properties and for this reason they could contribute to decrease the problem of microbial resistance to antibiotics. Elsevier 2017-05 2016-03-26 /pmc/articles/PMC5415143/ /pubmed/28490960 http://dx.doi.org/10.1016/j.sjbs.2016.03.005 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Bel Hadj Salah-Fatnassi, Karima
Hassayoun, Faten
Cheraif, Imed
Khan, Saba
Jannet, Hichem Ben
Hammami, Mohamed
Aouni, Mahjoub
Harzallah-Skhiri, Fethia
Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia
title Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia
title_full Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia
title_fullStr Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia
title_full_unstemmed Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia
title_short Chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of Santolina chamaecyparissus L., growing wild in Tunisia
title_sort chemical composition, antibacterial and antifungal activities of flowerhead and root essential oils of santolina chamaecyparissus l., growing wild in tunisia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415143/
https://www.ncbi.nlm.nih.gov/pubmed/28490960
http://dx.doi.org/10.1016/j.sjbs.2016.03.005
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