The transcriptional regulation of the human angiotensinogen gene after high-fat diet is haplotype-dependent: Novel insights into the gene-regulatory networks and implications for human hypertension

Single nucleotide polymorphisms (SNPs) in the human angiotensinogen (hAGT) gene may modulate its transcription and affect the regulation of blood pressure via activation of the renin-angiotensin aldosterone system (RAAS). In this regard, we have identified polymorphisms in the 2.5 Kb promoter of the...

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Detalles Bibliográficos
Autores principales: Rana, Anita, Jain, Sudhir, Puri, Nitin, Kaw, Meenakshi, Sirianni, Natalie, Eren, Deniz, Mopidevi, Brahma Raju, Kumar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415177/
https://www.ncbi.nlm.nih.gov/pubmed/28467442
http://dx.doi.org/10.1371/journal.pone.0176373

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