A fully automated procedure for the parallel, multidimensional purification and nucleotide loading of the human GTPases KRas, Rac1 and RalB

Small GTPases regulate many key cellular processes and their role in human disease validates many proteins in this class as desirable targets for therapeutic intervention. Reliable recombinant production of GTPases, often in the active GTP loaded state, is a prerequisite for the prosecution of drug...

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Detalles Bibliográficos
Autores principales: Gray, Christopher H., Konczal, Jennifer, Mezna, Mokdad, Ismail, Shehab, Bower, Justin, Drysdale, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415301/
https://www.ncbi.nlm.nih.gov/pubmed/28137655
http://dx.doi.org/10.1016/j.pep.2017.01.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415301/
https://www.ncbi.nlm.nih.gov/pubmed/28137655
http://dx.doi.org/10.1016/j.pep.2017.01.010

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