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Epigenetic stress responses induce muscle stem cell aging by Hoxa9 developmental signals
The functionality of stem cells declines during aging thereby contributing to aging-associated impairments in tissue regeneration and function(1). Alterations in developmental pathways have been associated with declines in stem cell function during aging(2–6) but the nature of this process remains p...
Autores principales: | Schwoerer, Simon, Becker, Friedrich, Feller, Christian, Baig, Ali H., Koeber, Ute, Henze, Henriette, Kraus, Johann M., Xin, Beibei, Lechel, André, Lipka, Daniel B., Varghese, Christy S., Schmidt, Manuel, Rohs, Remo, Aebersold, Ruedi, Medina, Kay L., Kestler, Hans A., Neri, Francesco, von Maltzahn, Julia, Tuempel, Stefan, Rudolph, K. Lenhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415306/ https://www.ncbi.nlm.nih.gov/pubmed/27919074 http://dx.doi.org/10.1038/nature20603 |
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