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Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes

Ex vivo transduction of human CD34(+) hematopoietic stem/progenitor cells (hCD34(+) HSPCs) and T lymphocytes is a key process that requires high efficiency and low toxicity to achieve effective clinical results. So far, several enhancers have been used to improve this process. Among them, Retronecti...

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Detalles Bibliográficos
Autores principales: Piovan, Claudia, Marin, Virna, Scavullo, Cinzia, Corna, Stefano, Giuliani, Erica, Bossi, Sergio, Galy, Anne, Fenard, David, Bordignon, Claudio, Rizzardi, Gian Paolo, Bovolenta, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415310/
https://www.ncbi.nlm.nih.gov/pubmed/28480301
http://dx.doi.org/10.1016/j.omtm.2017.02.003

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