Cargando…
Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes
Ex vivo transduction of human CD34(+) hematopoietic stem/progenitor cells (hCD34(+) HSPCs) and T lymphocytes is a key process that requires high efficiency and low toxicity to achieve effective clinical results. So far, several enhancers have been used to improve this process. Among them, Retronecti...
Autores principales: | Piovan, Claudia, Marin, Virna, Scavullo, Cinzia, Corna, Stefano, Giuliani, Erica, Bossi, Sergio, Galy, Anne, Fenard, David, Bordignon, Claudio, Rizzardi, Gian Paolo, Bovolenta, Chiara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415310/ https://www.ncbi.nlm.nih.gov/pubmed/28480301 http://dx.doi.org/10.1016/j.omtm.2017.02.003 |
Ejemplares similares
-
RD-MolPack technology for the constitutive production of self-inactivating lentiviral vectors pseudotyped with the nontoxic RD114-TR envelope
por: Marin, Virna, et al.
Publicado: (2016) -
Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein
por: Zucchelli, Eleonora, et al.
Publicado: (2017) -
Vectofusin-1, a New Viral Entry Enhancer, Strongly Promotes Lentiviral Transduction of Human Hematopoietic Stem Cells
por: Fenard, David, et al.
Publicado: (2013) -
Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System Manufacturing
por: Radek, Constanze, et al.
Publicado: (2019) -
Simultaneous Analysis of Secondary Structure and Light Scattering from Circular Dichroism Titrations: Application to Vectofusin-1
por: Vermeer, Louic S., et al.
Publicado: (2016)