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SWELL1 is a regulator of adipocyte size, insulin signaling and glucose homeostasis
Adipocytes undergo considerable volumetric expansion in the setting of obesity. It has been proposed that such marked increases in adipocyte size may be sensed via adipocyte-autonomous mechanisms to mediate size-dependent intracellular signaling. Here, we show that SWELL1 (LRRC8a), a member of the L...
Autores principales: | Zhang, Yanhui, Xie, Litao, Gunasekar, Susheel K., Tong, Dan, Mishra, Anil, Gibson, William J., Wang, Chuansong, Fidler, Trevor, Marthaler, Brodie, Klingelhutz, Aloysius, Abel, E. Dale, Samuel, Isaac, Smith, Jessica K., Cao, Lei, Sah, Rajan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415409/ https://www.ncbi.nlm.nih.gov/pubmed/28436964 http://dx.doi.org/10.1038/ncb3514 |
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