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The Protein Chaperone ClpX Targets Native and Non-native Aggregated Substrates for Remodeling, Disassembly, and Degradation with ClpP
ClpX is a member of the Clp/Hsp100 family of ATP-dependent chaperones and partners with ClpP, a compartmentalized protease, to degrade protein substrates bearing specific recognition signals. ClpX targets specific proteins for degradation directly or with substrate-specific adaptor proteins. Native...
Autores principales: | LaBreck, Christopher J., May, Shannon, Viola, Marissa G., Conti, Joseph, Camberg, Jodi L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415555/ https://www.ncbi.nlm.nih.gov/pubmed/28523271 http://dx.doi.org/10.3389/fmolb.2017.00026 |
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