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A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation
Mammalian limb development is driven by the integrative input from several signaling pathways; a failure to receive or a misinterpretation of these signals results in skeletal defects. The brachydactylies, a group of overlapping inherited human hand malformation syndromes, are mainly caused by mutat...
Autores principales: | Bernatik, Ondrej, Radaszkiewicz, Tomasz, Behal, Martin, Dave, Zankruti, Witte, Florian, Mahl, Annika, Cernohorsky, Nicole H., Krejci, Pavel, Stricker, Sigmar, Bryja, Vitezslav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415574/ https://www.ncbi.nlm.nih.gov/pubmed/28523267 http://dx.doi.org/10.3389/fcell.2017.00047 |
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