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Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice
BACKGROUND: Kososan, a Kampo (traditional Japanese herbal) medicine, has been used for the therapy of depressive mood in humans. However, evidence for the antidepressant efficacy of kososan and potential mechanisms are lacking. Recently, it has been recognized that stress triggers neuroinflammation...
Autores principales: | Ito, Naoki, Hirose, Eiji, Ishida, Tatsuya, Hori, Atsushi, Nagai, Takayuki, Kobayashi, Yoshinori, Kiyohara, Hiroaki, Oikawa, Tetsuro, Hanawa, Toshihiko, Odaguchi, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415730/ https://www.ncbi.nlm.nih.gov/pubmed/28468634 http://dx.doi.org/10.1186/s12974-017-0876-8 |
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