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Recombinant Salmonella expressing SspH2-EscI fusion protein limits its colonization in mice
BACKGROUND: Activation of inflammasome contributes to the clearance of intracellular bacteria. C-terminus of E. coli EscI protein can activate NLRC4 (NLR family, CARD domain containing-4) inflammasome in macrophages. The purpose of this study was to determine if activation of NLRC4 inflammasome by E...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415771/ https://www.ncbi.nlm.nih.gov/pubmed/28468643 http://dx.doi.org/10.1186/s12865-017-0203-2 |