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Recombinant Salmonella expressing SspH2-EscI fusion protein limits its colonization in mice

BACKGROUND: Activation of inflammasome contributes to the clearance of intracellular bacteria. C-terminus of E. coli EscI protein can activate NLRC4 (NLR family, CARD domain containing-4) inflammasome in macrophages. The purpose of this study was to determine if activation of NLRC4 inflammasome by E...

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Detalles Bibliográficos
Autores principales: Hu, Maozhi, Zhao, Weixin, Gao, Wei, Li, Wenhua, Meng, Chuang, Yan, Qiuxiang, Wang, Yuyang, Zhou, Xiaohui, Geng, Shizhong, Pan, Zhiming, Cui, Guiyou, Jiao, Xinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415771/
https://www.ncbi.nlm.nih.gov/pubmed/28468643
http://dx.doi.org/10.1186/s12865-017-0203-2