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Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue
BACKGROUND: DNA methylation is an important epigenetic mechanism involved in gene regulation, with alterations in DNA methylation in the nuclear genome being linked to numerous complex diseases. Mitochondrial DNA methylation is a phenomenon that is receiving ever-increasing interest, particularly in...
Autores principales: | Devall, Matthew, Smith, Rebecca G., Jeffries, Aaron, Hannon, Eilis, Davies, Matthew N., Schalkwyk, Leonard, Mill, Jonathan, Weedon, Michael, Lunnon, Katie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415779/ https://www.ncbi.nlm.nih.gov/pubmed/28473874 http://dx.doi.org/10.1186/s13148-017-0337-3 |
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