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ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype

BACKGROUND: Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists. It is caused by inactivating mutations in the gene encoding for the ATP-binding cassette, sub-family C member 6 t...

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Detalles Bibliográficos
Autores principales:	Miglionico, Rocchina, Ostuni, Angela, Armentano, Maria Francesca, Milella, Luigi, Crescenzi, Elvira, Carmosino, Monica, Bisaccia, Faustino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415800/ https://www.ncbi.nlm.nih.gov/pubmed/28536638 http://dx.doi.org/10.1186/s11658-017-0036-2

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