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MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis

BACKGROUND: Atherosclerosis is a chronically inflammatory disease and one of the leading causes of deaths worldwide. Endothelial cell apoptosis plays a crucial role in its development. Several microRNAs (miRNAs) are reportedly involved in atherosclerotic plaque formation, including miRNA-210 (miR-21...

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Detalles Bibliográficos
Autores principales: Li, Ying, Yang, Chunyan, Zhang, Lili, Yang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415835/
https://www.ncbi.nlm.nih.gov/pubmed/28536634
http://dx.doi.org/10.1186/s11658-017-0033-5