Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel ‘close, dock, lock and latch' mechanism for complement evasion

Complement factor H (CFH) is a soluble complement regulatory protein essential for the down-regulation of the alternative pathway on interaction with specific markers on the host cell surface. It recognizes the complement component 3b (C3b) and 3d (C3d) fragments in addition to self cell markers (i....

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Detalles Bibliográficos
Autores principales: Zhang, Yingjie, Wu, Minhao, Hang, Tianrong, Wang, Chengliang, Yang, Ye, Pan, Weimin, Zang, Jianye, Zhang, Min, Zhang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415847/
https://www.ncbi.nlm.nih.gov/pubmed/28258151
http://dx.doi.org/10.1042/BCJ20170085

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