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The role of miR-320a and IL-1β in human chondrocyte degradation

OBJECTIVES: This study aimed to explore the role of miR-320a in the pathogenesis of osteoarthritis (OA). METHODS: Human cartilage cells (C28/I2) were transfected with miR-320a or antisense oligonucleotides (ASO)-miR-320a, and treated with IL-1β. Subsequently the expression of collagen type II alpha...

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Detalles Bibliográficos
Autores principales: Jin, Y., Chen, X., Gao, Z. Y., Liu, K., Hou, Y., Zheng, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415906/
https://www.ncbi.nlm.nih.gov/pubmed/28404547
http://dx.doi.org/10.1302/2046-3758.64.BJR-2016-0224.R1