TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway

Mechanisms regulating the transition of mammary epithelial cells (MECs) to mammary stem cells (MaSCs) and to tumor-initiating cells (TICs) have not been entirely elucidated. The p53 family member, p63, is critical for mammary gland development and contains transactivation domain isoforms, which have...

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Detalles Bibliográficos
Autores principales: Su, X, Napoli, M, Abbas, H A, Venkatanarayan, A, Bui, N H B, Coarfa, C, Gi, Y J, Kittrell, F, Gunaratne, P H, Medina, D, Rosen, J M, Behbod, F, Flores, E R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415945/
https://www.ncbi.nlm.nih.gov/pubmed/27869165
http://dx.doi.org/10.1038/onc.2016.388

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