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Sustained Inhibition of HBV Replication In Vivo after Systemic Injection of AAVs Encoding Artificial Antiviral Primary MicroRNAs
Chronic infection with hepatitis B virus (HBV) remains a problem of global significance and improving available treatment is important to prevent life-threatening complications arising in persistently infected individuals. HBV is susceptible to silencing by exogenous artificial intermediates of the...
Autores principales: | Maepa, Mohube Betty, Ely, Abdullah, Grayson, Wayne, Arbuthnot, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415967/ https://www.ncbi.nlm.nih.gov/pubmed/28624194 http://dx.doi.org/10.1016/j.omtn.2017.04.007 |
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