Cargando…

RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT

BACKGROUND: The acute kidney injury (AKI) may do damage to remote organs. Objective of the study is to investigate effect of seaweed extract (SE) on brain oxidative damage in kidney ischemia/reperfusion rats. MATERIAL AND METHODS: Animals were randomly divided into five groups. SE pre-fed to rats. R...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Fang, Liang, Haidong, Xin, Shimeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: African Traditional Herbal Medicine Supporters Initiative (ATHMSI) 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416646/
https://www.ncbi.nlm.nih.gov/pubmed/28487895
http://dx.doi.org/10.21010/ajtcam.v13i5.9
_version_ 1783233788134817792
author Yu, Fang
Liang, Haidong
Xin, Shimeng
author_facet Yu, Fang
Liang, Haidong
Xin, Shimeng
author_sort Yu, Fang
collection PubMed
description BACKGROUND: The acute kidney injury (AKI) may do damage to remote organs. Objective of the study is to investigate effect of seaweed extract (SE) on brain oxidative damage in kidney ischemia/reperfusion rats. MATERIAL AND METHODS: Animals were randomly divided into five groups. SE pre-fed to rats. RESULTS: Kidney I/R may cause oxidative injury in kidneys and brains tissue in rats. SE pre-treatment can decrease lipid peroxidation levels and increase antioxidant enzymes activities in kidney and brain hippocampus of kidney I/R rats. CONCLUSION: Our results indicate that SE is useful for brain nerve function keeping in kidney I/R rats.
format Online
Article
Text
id pubmed-5416646
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher African Traditional Herbal Medicine Supporters Initiative (ATHMSI)
record_format MEDLINE/PubMed
spelling pubmed-54166462017-08-12 RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT Yu, Fang Liang, Haidong Xin, Shimeng Afr J Tradit Complement Altern Med Article BACKGROUND: The acute kidney injury (AKI) may do damage to remote organs. Objective of the study is to investigate effect of seaweed extract (SE) on brain oxidative damage in kidney ischemia/reperfusion rats. MATERIAL AND METHODS: Animals were randomly divided into five groups. SE pre-fed to rats. RESULTS: Kidney I/R may cause oxidative injury in kidneys and brains tissue in rats. SE pre-treatment can decrease lipid peroxidation levels and increase antioxidant enzymes activities in kidney and brain hippocampus of kidney I/R rats. CONCLUSION: Our results indicate that SE is useful for brain nerve function keeping in kidney I/R rats. African Traditional Herbal Medicine Supporters Initiative (ATHMSI) 2016-08-12 /pmc/articles/PMC5416646/ /pubmed/28487895 http://dx.doi.org/10.21010/ajtcam.v13i5.9 Text en Copyright: © 2016 Afr. J. Traditional Complementary and Alternative Medicines http://creativecommons.org/licenses/CC-BY/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
spellingShingle Article
Yu, Fang
Liang, Haidong
Xin, Shimeng
RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT
title RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT
title_full RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT
title_fullStr RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT
title_full_unstemmed RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT
title_short RENAL ISCHEMIA REPERFUSION CAUSES BRAIN HIPPOCAMPUS OXIDATIVE DAMAGE AND INHIBITION EFFECT
title_sort renal ischemia reperfusion causes brain hippocampus oxidative damage and inhibition effect
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416646/
https://www.ncbi.nlm.nih.gov/pubmed/28487895
http://dx.doi.org/10.21010/ajtcam.v13i5.9
work_keys_str_mv AT yufang renalischemiareperfusioncausesbrainhippocampusoxidativedamageandinhibitioneffect
AT lianghaidong renalischemiareperfusioncausesbrainhippocampusoxidativedamageandinhibitioneffect
AT xinshimeng renalischemiareperfusioncausesbrainhippocampusoxidativedamageandinhibitioneffect